Semaglutide Dosage Guide
Complete dosing protocol for Semaglutide including recommended doses, frequency, timing, and important considerations.
Recommended Dosing
- Dose Range: 250-2500 mcg
- Frequency: 1x per week
- Timing: Same day each week, any time of day
- Half-Life: ~7 days
Important Notes
Start low (250mcg/week) and titrate up slowly over 4-8 weeks. Nausea is common when starting.
About Semaglutide
Semaglutide is an FDA-approved GLP-1 receptor agonist originally developed for Type 2 diabetes (Ozempic) and later approved for chronic weight management (Wegovy). It mimics the hormone GLP-1, which regulates appetite, food intake, and blood sugar levels. Clinical trials have demonstrated impressive weight loss results, with participants losing an average of 15-17% of body weight over 68 weeks. Semaglutide works by slowing gastric emptying, reducing appetite, and improving insulin sensitivity. It also shows cardiovascular benefits, reducing major adverse cardiac events in at-risk patients. The once-weekly dosing makes it convenient compared to daily alternatives.
Dosage Calculator | Reconstitution Guide | Stack Guide | Shop