Ipamorelin vs CJC-1295 (with DAC)

A detailed side-by-side comparison of Ipamorelin and CJC-1295 (with DAC) covering dosing, storage, research findings, and practical usage.

Overview

Ipamorelin: A selective GH secretagogue with minimal effect on cortisol or prolactin.

CJC-1295 (with DAC): A GHRH analog with Drug Affinity Complex for extended half-life.

Comparison Table

PropertyIpamorelinCJC-1295 (with DAC)
CategoryGrowth Hormone SecretagogueGrowth Hormone Secretagogue
Typical Dose100-300 mcg1000-2000 mcg
Frequency2-3x daily1-2x per week
Half-Life2-3 hours6-8 days
TimingMorning fasted, post-workout, and before bed (fasted 2+ hours)Any time, often at night

Ipamorelin Research

Ipamorelin is a synthetic pentapeptide that acts as a selective growth hormone secretagogue. Unlike other GHRPs, ipamorelin specifically stimulates growth hormone release without significantly affecting cortisol, prolactin, or aldosterone levels, making it one of the cleanest GH-releasing peptides available. Research shows it provides a controlled, dose-dependent GH pulse similar to natural secretion patterns. Studies demonstrate benefits for body composition, sleep quality, and recovery. Ipamorelin is often combined with CJC-1295 (no DAC) for synergistic effects, as they work through complementary pathways (GHRP + GHRH).

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